The Effect of Ultrasound-Microwave Assisted Extraction (UAE-MAE) Method on the Antioxidant Activity of Ethyl Acetate Extract of Bajakah Roots (Spatholobus Littoralis Hassk) Using DPPH Method

Muchammad Reza Ghozaly; Berna Elya; Muhammad Hanafi; Heri Setiawan

doi:10.55927/fjst.v4i3.38

Authors

Muchammad Reza Ghozaly Department of Phytochemistry and Pharmacognosy, Faculty of Pharmacy, Universitas Indonesia
Berna Elya Department of Phytochemistry and Pharmacognosy, Faculty of Pharmacy, Universitas Indonesia
Muhammad Hanafi Research Centre for Pharmaceutical Ingredients and Traditional Medicine, National Research and Innovation Agency (BRIN)
Heri Setiawan Department of Pharmacology, Faculty of Pharmacy, Universitas Indonesia

DOI:

https://doi.org/10.55927/fjst.v4i3.38

Keywords:

Bajakah, Spatholobus Littoralis Hassk, UAE-MAE, DPPH, Antioxidant

Abstract

The roots of Spatholobus littoralis Hassk, obtained from Central Kalimantan, were extracted using a combined ultrasound-microwave-assisted extraction method with ethyl acetate as the solvent. The results demonstrated potent antioxidant activity, with an IC₅₀ value of 43.18 µg/mL, which correlates with the total flavonoid content (26.85 ± 0.059 mgQE/g) and total phenolic content (145.152 ± 0.04 mgGAE/g). Although vitamin C exhibited higher activity (IC₅₀ 2.71 µg/mL), S. littoralis roots still hold significant potential as a natural antioxidant source.

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